Connecting Business. Strengthening Community.

The Greater Hyannis Chamber of Commerce brings businesses, people, and opportunities together in the heart of Cape Cod. Based on historic Main Street in Hyannis, we proudly represent the diverse business community across the Town of Barnstable’s seven distinctive villages.

As a nonprofit 501(c)(6) organization, we champion local businesses through strategic marketing, meaningful networking, advocacy, and economic development initiatives. By connecting business leaders, government, and community partners, we support a strong local economy and help shape Barnstable’s future.

We’re also a trusted resource for residents and visitors—a welcoming place to find local insight, discover businesses, and explore everything our community has to offer. Whether you’re growing a business, planning a visit, or getting to know the place you call home, the Chamber helps you make the connections that matter.

Our mission is simple: to make Barnstable an exceptional place to live, work, and visit.

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Celebrate the season at Breakfast with Santa, hosted by the Greater Hyannis Chamber of Commerce at the Comfort Inn Hyannis! Bring the family for a delicious breakfast buffet, a visit with Santa, and plenty of holiday cheer. Children can share their Christmas wishes, and families can capture special moments—so bring your camera! It’s the perfect way to kick off a festive day at the Hyannis Main Street Holiday Stroll. Seating is limited, so explore the event details and reserve your tickets today!

TO REGISTER CLICK HERE.